His recent writing and production credits include Kylie Minogue, Chris Malinchak, Bondax, Becky Hill, Oliver Heldens, Karen Harding, Tieks, Zara Larsson, Naughty Boy, Gorgon City, Sub Focus, Clean Bandit, Duke Dumont, Rudimental, Little Mix, A*M*E among others and his remixes include Duran Duran, Olly Murs, Bastille and Tinie Tempah. He has also contributed vocals on the song "Living for Love" by Madonna.
In February 2012, he featured on Rudimental's single "Spoons" with Syron. The song features on their debut studio album Home (2013). In December 2013 he was one of 15 artists to make BBC's long list. In January 2014 he featured on Gorgon City's single "Ready for Your Love". The song peaked to number 4 on the UK Singles Chart. On 20 April 2014, he premiered "Every Little Word" on 1Xtra, the "buzz" single from his debut studio album.
On 9 May the remix EP featuring Joe Goddard and Fred V & Grafix among others was released. Emenike has said we can expect to hear collaborations with Moko, Snakehips and Jimmy Napes on the record. The lead single "Wrote a Song About You" premiered on Annie Mac's BBC Radio 1 show on 13 June 2014. In June 2014, Oliver Heldens' track Gecko, which Emenike wrote, debuted at number 1 on both the UK Dance Chart and the UK Singles Chart. MNEK produced the song "Feels So Good" by Kylie Minogue, from her album Kiss Me Once. On 22 July, Emenike released the promotional single "In Your Clouds" as part of an iTunes Ones to Watch campaign. The song will feature on his debut album. In 2014, he worked with Madonna in her album, Rebel Heart. His debut extended play Small Talk was released on 20 March 2015. In March 2015, JoJo announced that she worked with MNEK on her new studio album.