After forming in 1994, the band released three albums. Paranoid & Sunburnt, Stoosh and Post Orgasmic Chill sold over 4 million copies worldwide. They are best known for their single "Weak", but have had a series of other hits including "Charity", "Hedonism" and "Charlie Big Potato".
In 2001 the band decided to split. Ace released a solo album entitled Still Hungry, Mark became a replacement drummer for the band Feeder and Skin went on to pursue a solo career.
In 2008 drummer Mark Richardson confirmed reports that the band was reforming in an interview with Drummer Magazine (2008, November Issue), and said that the band planned to release a 'Best Of' as well as new material.
After Skunk Anansie split, Skin released her debut solo album Fleshwounds. The album was toned down from her Skunk Anansie days and did not gain the same acclaim from Skunk Anansie fans. She even ditched her trademark bald look and grew her hair into a boyish crop. While the album was not a massive success in the UK, two singles were released from it: "Trashed" and "Faithfulness". "Lost", a double A-Side with "Getting Away With It", was a planned third single but was pulled shortly before release; promo CDs were sent out to radio stations but it received no airplay. Elsewhere in Europe the album's success was greater. For example, in Italy it peaked at #6 in the album chart, and in Germany it peaked at #18.
After releasing Fleshwounds, Skin went on to perform various solo gigs around Europe. She was also support for the European leg of Robbie Williams' and Placebo's world tours.
Soon after touring she began to record her second album, Fake Chemical State, which was released for sale on 20 March 2006, preceded by new single Just Let the Sun two weeks earlier. The first single actually issued from this album was Alone in My Room, a download-only track released on 7 November 2005. 'Alone In My Room' was also the name given to Skin's first UK solo tour in two years, which commenced in Berlin in November 2005. For this album she shaved her head bald again, returning to the look she had in her Skunk Anansie days.
Skin's next solo outing was a small promotional 'Fake Chemical State' tour. It started in Glasgow on 17 March 2006. She went onto perform many festivals around Europe including Rock Werchter in Belgium and the Southside/Hurricane festivals in Germany. She performed on the main stage at most of these festivals.
In February 2008 she announced that she was working with Timo Maas and Martin Buttrich on a side project called "Format-3". Her 2008 song "Tear Down These Houses" was released as a part of the soundtrack to Parlami d'Amore, directed by Silvio Muccino.